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DNA damage in sea stars

A truly amazing application of the comet assay: investigation into the regeneration of lost body parts in the sea star, Asterias rubens.  Researchers in Sweden and Norway propose a new working hypothesis for arm regeneration in sea stars. 

The comet assay and the ultra-marathon

To determine if six weeks of diet-supplementation with antioxidants could alleviate exercise-induced DNA damage, 21 runners completing a 50 km ultra-marathon were studied. The comet assay was the tool of choice for determining DNA damage.

Antimutagenic properties of grape seeds

Mahidol University and The Thailand Institute of Scientific and Technological Research have been working together in collaboration to investigate the biological properties of oligomeric proanthocyanidins (OPCs) which are found in red grape seeds.

Biomonitoring pottery workers

An increased risk for occupational lead exposure occurs among pottery and ceramic industry workers. A study based in Croatia used the comet assay in the biomonitoring investigation.

Green vegetables reduce cancer risk

Epidemiological studies indicate that consumption of green-yellow vegetables rich in chlorophyll, vitamin C, vitamin E and carotenoids reduce the risk of cancer. Here, using the comet assay, it was shown that plant extracts protected against H2O2-induced genotoxic damage in human HCT116 colon cancer cells.