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Comet assay news

Protocol to evaluate DNA damage in whole nematodes using the comet assay

 The scientists at King’s College, London, and their collaborators have been working to establish a protocol for cell dissociation from the nematode Caenorhabditis elegans.  They are using the comet assay to assess BaP genotoxicity.

Turkish folklore & “healing” plants

Dried fruits of Berberis crataegina (Berberidaceae) have been frequently consumed in Turkish cuisine and a selection of Turkish scientists decided to investigate some of the ‘healing properties’ linked to this fruit and evaluate any possible risks.

Reference cells and mixed-ploidy cells in the comet assay

 Scientists at the University of Oslo and Norwegian Institute of Public Health (both based in Oslo, Norway) have been investigating the use of “reference cells” within the comet assay.  They also performed the comet assay on a mixture of testicular cells with various ploidy.

HepG2 cells under silver nanoparticle-induced stress - comet assay investigation

 Scientists in Poland have been investigating the adaptation of HepG2 cells to silver nanoparticle-induced stress.  They found that the adaptation is based on the pro-proliferative and anti-apoptotic changes in gene expression. 

Resveratrol & the comet assay

Researchers from the Department of Food Chemistry and Toxicology at the University of Vienna have been exploring whether Resveratrol, a naturally occurring polyphenol, modulates the topoisomerase inhibitory potential of doxorubicin in a human cell line.