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Comet Assay IV

An innovation in cell scoring

Comet Assay IVTM is the latest in a highly successful series of comet scoring systems originally developed by Perceptive Instruments, now a part of Instem. Comet Assay IV is the professional choice for those seeking accuracy, reproducibility and GLP compliance.

Getting started with Comet Assay IV is as simple as installing the software and connecting the camera.This can be done in a few minutes either by yourself or your IT department. Once running, Comet Assay IV displays a live video image onscreen that mirrors what you see by looking down the microscope's eyepiece. Any refocusing or stage movements performed at the microscope level are shown live on screen without any lag or delay.



Scoring with Comet Assay IV is a uniquely effortless process. Just click on each comet to get your results.

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Comet Assay IV's flexible study management makes it easy to implement the system within your existing framework.

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Report and graph your results in Excel with the Spreadsheet Generator.

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With audit trails, forced entry of reasons for edits, deletes etc. and electronic signature options.

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  • All major measurement parameters

  • Score a slide in two minutes

  • Windows 10 64-bit compatibility

  • Oracle database connectivity

  • Inbuilt hedgehog counter

  • Comprehensively tested and validated

  • One year Standard Support Maintenance Contract included

  • Free one week trial version


We have found the Comet Assay IV software very useful and convenient.

Research Scientist, Food Safety Agency, France

We are very happy with everything, it is easy to work with your software.

Senior Scientist, National Health Institute, Portugal

We are very satisfied with your software.

Scientist, Cancer Research Institute, Slovakia

It is actually working great.

Professor, University, USA

We started using Comet Assay IV and it works well...

Researcher, Nuclear Agency, France

Thanks for your attention and great service. I am so glad that we have Comet IV.

Study Director, Contract Research Organisation, USA

We have had no problems so far, and we are very pleased with the system.

Senior Researcher, Public Health Agency, Finland

I have been using the Comet Assay IV Software. It is great! During my software validation, I realized how much easier and precise it is compared to our old software. It makes analyzing the comet slides more enjoyable

Scientist, Medical Research Centre, USA

It is, indeed, much quicker than the old image analysis system that we had. We are very pleased with it.

Senior Researcher, Public Health Agency, Finland

The Comet Assay IV system we already installed and is working perfectly.

Scientist, Environmental Institute, Norway

We're now using the software and it works great. It has cut our time for comets by at least half.

Post Doctoral Fellow, National Institute of Health, USA

We have installed the software and are using it without any problem. It's really simple! My PhD students are very happy with it.

Professor, University, Spain

The system is working great.

Senior Research Scientist, Cancer Research Institute, UK

I'm really a fan of your system :)

Genetic Toxicologist, Global Pharmaceutical Company

All is going well and the more I use the software the more I love the way it's so simple and intuitive...the comet software is running well and in increasing use.

Scientist, University, UK

...and the system is running great.

Medical Researcher, Cancer Research Institute, USA

Perfect and very clear installation and training!

Researcher, Contract Testing Laboratory, Europe

It's an amazing program! Really useful!

Research Scientist, University, Brazil

We are really very happy with the comet analysis system.

Research Scientist, University, Austria

We are impressed indeed! It has saved us quite a lot of time and pains.

Director, Toxicology Research Centre, Spain

Everything has gone very well with the system and we are very pleased with it.

Professor, University, UK

...we are "happy users" of the software

Senior Researcher, Risk Assessment Institute, Germany

...have been using it now for a couple of weeks and it seems to be working great. Very user friendly - I love it as does my intern!

Staff Chemist, Marine Laboratory, USA

Excellent, perfectly straightforward.

Scientist, University, UK

Yes, it is very useful and we are in the process of writing a paper also from the data derived from Comet Assay IV.

Assistant Professor, University, USA

The system is up and running. Everybody is impressed with the speed of scoring slides.

Researcher, University, South Africa

Total change in our lab since you came (with Comet Assay IV of course...)! thanks... :-)

Postgraduate Researcher, University, France

I love the software. Keep up the good work over there.

Study Director, Contract Research Organisation, USA

...Everything is fine with the Comet Assay IV system...and I'm pretty happy about this new software with just clicking on the cells instead of drawing a frame around them

Researcher, Cancer Research Organisation, UK

Excellent, the training was very helpful and specific to in-house technicalities.

Lecturer, University, UK

Comet Assay IV software is in use. Currently our comet analysis is based on tail moment measurement and I must say that everything works properly.

Researcher, Cancer Research Institute, Slovakia

Everything has gone very well with the system and we are very pleased with it.

Scientist, University, UK

The installation was quick and all the details were described and easily understandable for the technicians.

Head of Department, Global Chemical Company, Germany

I don't have any questions about the software as it has worked quite well for us...so far we are very happy with the software.

Research Scientist, University, Australia

We have just recently utilized the system and are extremely pleased.

Assistant Professor, University, USA

Just to let you know we have started the validation study for Comet Assay IV and it has been going very well! We ran a comet assay last week and scored the slides with no problems at all. I am very pleased with the system and it will certainly make a difference when we run some comet studies this year!

Study Director, Food & Household Products Company, UK

So far, I'm very happy with the system.

Research Lecturer, University, UK

The system was set up last month, and so far it works very well. Both my boss and I are very satisfied with it and like it very much.

Researcher, University Hospital, Germany

Perfect and very clear installation and training.

Study Director, Contract Research Organisation, Europe

So it's working out fine and we're very happy!

Toxicologist, Health Agency, Canada

The current Comet Assay IV system works without any trouble…we are pleased with the system.

Scientist, Chemical Company, Japan