Comet Assay IV Publications
Perceptive Instruments Comet Assay IV image analysis systems have been sited within peer-reviewed publications hundreds of times. Here, we have listed a few of them:
Papers from 2011
A protocol for the evaluation of genotoxicity in bile of carp (Cyprinus carpio) exposed to lake water treated with different disinfectants
(2011) M. Villarini et al, Chemosphere 84(10):1521-1526
Acellular comet assay: a tool for assessing variables influencing the alkaline comet assay
(2011) E Kennedy et al, Radiat Prot Dosimetry (E-pub ahead of print)
Acrylamide genotoxicity in young versus adult gpt delta male rats
(2011) N. Koyama et al, Mutagenesis 26(4):545-549
Papers from 2010
A multibiomarker approach in Coris julis living in a natural environment
(2010) S. Fasulo et al, Ecototoxicol. and Environ. Safety
An ECVAG dagger trial on assessment of oxidative damage to DNA measured by the comet assay
(2010) C Johansson et al, Mutagenesis 25(2):125-132
Anomalous genotoxic responses induced in mouse lymphoma L5178Y cells by potassium bromate
(2010) C. Priestley et al, Toxicology 267(1-3):45-53
Papers from 2009
Below are a number of refereed papers from 2009 in which Perceptive Instruments software is used for the comet assay. Applications of the systems include research and testing in nutrition, medicine, biomonitoring and genetic toxicology:
Cytotoxicity and oxidative DNA damage by nanoparticles in human intestinal Caco-2 cells
(2009) K. Gerloff et al, Nanotoxicology 3(4): 355-364
Delphinidin Modulates the DNA-Damaging Properties of Topoisomerase II Poisons
(2009) M. Esselen et al, Chem. Res. Toxicol. 22(3):554-564
Genotoxicity evaluation of locally produced dental porcelain – An in vitro study using the Ames and Comet assays
(2009) M. Noushad et al., Toxicol In Vitro. 23(6):1145-50
Papers from 2008
Below are a number of refereed papers from 2008 in which Perceptive Instruments software is used for the comet assay. Applications of the systems include research and testing in nutrition, medicine, biomonitoring and genetic toxicology:
Alcohol induces DNA damage and the Fanconi anemia D2 protein implicating FANCD2 in the DNA damage response pathways in brain
(2008) S.L. Rulten et al, Alc. Clin. Exp. Res. 32(7):1186-1196
Analysis of DNA breaks, DNA damage response, and apoptosis produced by high NaCl
(2008) N.I. Dmitrieva et al, Am. J. Phys. Renal Phys. 295(1):1678-1688
Anthocyanin/Polyphenolic–Rich Fruit Juice Reduces Oxidative Cell Damage in an Intervention Study with Patients on Hemodialysis
(2008) T.M. Spormann et al, Canc. Epi. Biom. & Prev. 17(1):3372-3380
Papers from 2007
Below are a number of refereed papers from 2007 in which Perceptive Instruments software is used for the comet assay. Applications of the systems include potentially harmful and beneficial dietary factors; biomonitoring; molecular epidemiology; photobiology; mechanistic studies, clinical and dentistry.
8-Oxoguanine DNA Glycosylase and MutY Homolog Are Involved in the Incision of Arsenite-Induced DNA Adducts
(2007) Y. Pu et al, Tox. Sci. 95(2):376-382
Absence of DNA damage in multiple organs (blood, liver, kidney, thyroid gland and urinary bladder) after acute fluoride exposure in rats
(2007) A. de Lima Leite et al, Human & Expt. Tox. 26(5):435-440
An optimized method for detecting gamma-H2AX in blood cells reveals a significant interindividual variation in the gamma-H2AX response among humans
(2007) I. H. Ismail et al, Nuc. Acids Res. 35(5):e36
Papers from 2006
Below are a number of refereed papers from 2006 in which Perceptive Instruments software is used for the comet assay. Applications of the systems include genotoxicity testing of materials used in dentistry; potentially harmful and beneficial dietary factors; biomonitoring; molecular epidemiology; photobiology; mechanistic studies and clinical.
2-Dodecylcyclobutanone, a radiolytic product of palmitic acid, is genotoxic in primary human colon cells and in cells from preneoplastic lesions
(2006) N. Knoll et al, Mut. Res. 594(1-2):10-19
A Protease Pathway for the Repair of Topoisomerase II-DNA Covalent Complexes
(2006) A. Zhang et al, Journal of Biological Chemistry 281(47):35997-36003
Alkaline comet assay study with breast cancer patients: evaluation of baseline and chemotherapy-induced DNA damage in non-target cells
(2006) N. Kopjar et al, Clin. Exp. Med. 6(4):177-190
Papers from 2005
Below are a number of refereed papers from 2005 in which Perceptive Instruments software is used for the comet assay. Applications of the systems include research and testing in nutrition, medicine, biomonitoring and genetic toxicology:
Biocompatibility In Vitro Tests of Mineral Trioxide Aggregate and Regular and White Portland Cements
(2005) D.A. Ribeiro et al, Journal of Endodontics 31(8):605-607
The novel human gene aprataxin is directly involved in DNA single-strand-break repair
(2005) P. Mosesso et al, Cellular and Molecular Life Sciences 62(4):485-491
Genetic polymorphisms and the effect of cigarette smoking in the comet assay
(2005) H. Hoffmann et al, Mutagenesis 20(5):359-364