Single click automatic scoring

Live video technology

Comet Assay IV has the ability to score comets from a live video. This makes Comet Assay IV the fastest, easiest and most accurate way to score comets to date.

Comet Assay IV is supplied with a USB video camera delivering up to 3x the resolution of previous models. This makes it possible to use lower power microscope objectives, offering a larger field of view and greater depth of field.

This combination greatly improves scoring speed, with more comets per field and less time spent at the controls of the microscope.

Unrivalled productivity and reproducibility

Comet Assay IV introduces Click&Score - a revolutionary automatic scoring method in which a single click on a comet initiates & completes the entire measurement cycle, including background correction, determination of head and tail regions and computation of all parameters.

With Click&Score, you simply have to identify the comet to be scored with a single click of the mouse. This has productivity and reproducibility advantages over manual framing methods that require users to position a measurement frame around each individual cell.

Eliminate user subjectivity and bias

The Click&Score method does not require the configuration of any adjustable settings, thereby eliminating all subjectivity from the scoring process.

Click&Score automatically compensates for slides with uneven backgrounds or varying levels of brightness, ensuring comparable results across a wide range of slides; even highly damaged 'hedgehog' comets can be accurately and consistently measured.

In addition, to further remove user bias, measurements for each slide are viewable within a scrollable results window, which can be hidden entirely for those wishing to score blind.

Data security ensured during scoring

Once the desired number of cells has been scored with Comet Assay IV, the user is prompted to save the data to Microsoft Excel before moving on to score the next slide.

For additional security and GLP compliance, the system can be configured to send result data to an Oracle database.


I don't have any questions about the software as it has worked quite well for far we are very happy with the software.

Research Scientist, University, Australia

Thanks for your attention and great service. I am so glad that we have Comet IV.

Study Director, Contract Research Organisation, USA

I'm really a fan of your system :)

Genetic Toxicologist, Global Pharmaceutical Company

...have been using it now for a couple of weeks and it seems to be working great. Very user friendly - I love it as does my intern!

Staff Chemist, Marine Laboratory, USA

The Comet Assay IV system we already installed and is working perfectly.

Scientist, Environmental Institute, Norway

Comet Assay IV software is in use. Currently our comet analysis is based on tail moment measurement and I must say that everything works properly.

Researcher, Cancer Research Institute, Slovakia

I love the software. Keep up the good work over there.

Study Director, Contract Research Organisation, USA

Everything has gone very well with the system and we are very pleased with it.

Scientist, University, UK

We are really very happy with the comet analysis system.

Research Scientist, University, Austria

So it's working out fine and we're very happy!

Toxicologist, Health Agency, Canada

Just to let you know we have started the validation study for Comet Assay IV and it has been going very well! We ran a comet assay last week and scored the slides with no problems at all. I am very pleased with the system and it will certainly make a difference when we run some comet studies this year!

Study Director, Food & Household Products Company, UK

Excellent, the training was very helpful and specific to in-house technicalities.

Lecturer, University, UK

So far, I'm very happy with the system.

Research Lecturer, University, UK

Perfect and very clear installation and training!

Researcher, Contract Testing Laboratory, Europe

The current Comet Assay IV system works without any trouble…we are pleased with the system.

Scientist, Chemical Company, Japan

We have had no problems so far, and we are very pleased with the system.

Senior Researcher, Public Health Agency, Finland

Perfect and very clear installation and training.

Study Director, Contract Research Organisation, Europe

We're now using the software and it works great. It has cut our time for comets by at least half.

Post Doctoral Fellow, National Institute of Health, USA

I have been using the Comet Assay IV Software. It is great! During my software validation, I realized how much easier and precise it is compared to our old software. It makes analyzing the comet slides more enjoyable

Scientist, Medical Research Centre, USA

The installation was quick and all the details were described and easily understandable for the technicians.

Head of Department, Global Chemical Company, Germany

It's an amazing program! Really useful!

Research Scientist, University, Brazil

It is, indeed, much quicker than the old image analysis system that we had. We are very pleased with it.

Senior Researcher, Public Health Agency, Finland

...we are "happy users" of the software

Senior Researcher, Risk Assessment Institute, Germany

The system was set up last month, and so far it works very well. Both my boss and I are very satisfied with it and like it very much.

Researcher, University Hospital, Germany

We are using the Comet Assay IV a lot (and our use is increasing). It's working very well.

Professor, Children's Research Hospital, USA

Everything has gone very well with the system and we are very pleased with it.

Professor, University, UK

The system is up and running. Everybody is impressed with the speed of scoring slides.

Researcher, University, South Africa

We started using Comet Assay IV and it works well...

Researcher, Nuclear Agency, France

We are impressed indeed! It has saved us quite a lot of time and pains.

Director, Toxicology Research Centre, Spain

Total change in our lab since you came (with Comet Assay IV of course...)! thanks... :-)

Postgraduate Researcher, University, France

Yes, it is very useful and we are in the process of writing a paper also from the data derived from Comet Assay IV.

Assistant Professor, University, USA

We have just recently utilized the system and are extremely pleased.

Assistant Professor, University, USA

It is actually working great.

Professor, University, USA

We are very satisfied with your software.

Scientist, Cancer Research Institute, Slovakia

We have found the Comet Assay IV software very useful and convenient.

Research Scientist, Food Safety Agency, France

...and the system is running great.

Medical Researcher, Cancer Research Institute, USA

...Everything is fine with the Comet Assay IV system...and I'm pretty happy about this new software with just clicking on the cells instead of drawing a frame around them

Researcher, Cancer Research Organisation, UK

We are very happy with everything, it is easy to work with your software.

Senior Scientist, National Health Institute, Portugal

The system is working great.

Senior Research Scientist, Cancer Research Institute, UK

Excellent, perfectly straightforward.

Scientist, University, UK

We have installed the software and are using it without any problem. It's really simple! My PhD students are very happy with it.

Professor, University, Spain